Precision nutrition for cardiometabolic diseases
Guasch-Ferre, Marta Wittenbecher, Clemens Palmnas, Marie Ben-Yacov, Orly Blaak, Ellen E. Dahm, Christina C. Fall, Tove Heitmann, Berit L. Licht, Tine R. Lof, Marie
Guasch-Ferre, Marta
Wittenbecher, Clemens
Palmnas, Marie
Ben-Yacov, Orly
Blaak, Ellen E.
Dahm, Christina C.
Fall, Tove
Heitmann, Berit L.
Licht, Tine R.
Lof, Marie
Author
Guasch-Ferre, Marta
Wittenbecher, Clemens
Palmnas, Marie
Ben-Yacov, Orly
Blaak, Ellen E.
Dahm, Christina C.
Fall, Tove
Heitmann, Berit L.
Licht, Tine R.
Lof, Marie
Loos, Ruth
Patel, Chirag J.
Quarta, Carmelo
Redman, Leanne M.
Segal, Eran
Segata, Nicola
Snyder, Michael
Sun, Qi
Tobias, Deirdre K.
Hu, Frank B.
Franks, Paul W.
Landberg, Rikard
Sargent, Jennifer L.
Merino, Jordi
Wittenbecher, Clemens
Palmnas, Marie
Ben-Yacov, Orly
Blaak, Ellen E.
Dahm, Christina C.
Fall, Tove
Heitmann, Berit L.
Licht, Tine R.
Lof, Marie
Loos, Ruth
Patel, Chirag J.
Quarta, Carmelo
Redman, Leanne M.
Segal, Eran
Segata, Nicola
Snyder, Michael
Sun, Qi
Tobias, Deirdre K.
Hu, Frank B.
Franks, Paul W.
Landberg, Rikard
Sargent, Jennifer L.
Merino, Jordi
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Department
Computational Biology
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Journal article
Date
2025
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English
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Abstract
Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet. These studies illustrate the promise of precision nutrition to complement the traditional ‘one size fits all’ dietary guidelines, which, while considering broad life-stage and disease-specific nutritional requirements, often lack the granularity to account fully for individual variations in nutritional needs and dietary responses. Despite these developments, however, considerable challenges remain before precision nutrition can be implemented on a broader scale. This Review examines the current state of precision nutrition research, with a focus on its application to reducing the incidence and burden of cardiometabolic diseases. We critically examine the evidence base, explore the potential benefits and discuss the challenges and opportunities ahead.
Citation
M. Guasch-Ferré et al., “Precision nutrition for cardiometabolic diseases,” Nature Medicine 2025, pp. 1–10, Apr. 2025, doi: 10.1038/s41591-025-03669-9.
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Nature Medicine
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Springer Nature