Item

Design of MOSAAIC (Multi-Ethnic Observational Study in American Asian and Pacific Islander Communities)

Ahn, Jiyoung
; 
Ahsan, Habibul
; 
Anderson, Garnet L
; 
Aschebrook-Kilfoy, Briseis
; 
Beery, Danny
; 
Carrick, William
; 
Celedón, Juan C
; 
Chan, KC
; 
Chen, Yu
; 
Ðoàn, Lan N
... show 10 more
Author
Ahn, Jiyoung
Ahsan, Habibul
Anderson, Garnet L
Aschebrook-Kilfoy, Briseis
Beery, Danny
Carrick, William
Celedón, Juan C
Chan, KC
Chen, Yu
Ðoàn, Lan N
Fang, Carolyn Y
Floyd, James S
Hayes, Richard B
Henderson, Victor
Hong, Yuling
Hsing, Ann W
Hsu, Li
Hu, Frank B
Jin, Jingyu Linna
John, Esther M
Kanaya, Alka M
Kaplan, Robert C
Kibriya, Muhammad G
Kim, Karen
Kushida, Clete
Lampe, Johanna W
Li, ShangJu
Lu, Ying
X., Grace
Mau, Marjorie KLM
Maunakea, Alika K
Mendoza, Jason A
Neuhouser, Marian L
Newman, Jonathan D
Odden, Michelle C
Palaniappan, Latha
Park, S Lani
Randal, Fornessa
Rhew, Isaac C
Santos, Stephanie
Soliman, Elsayed Z
Thyagarajan, Bharat
Tsai, Jenny Hsin-Chun
VoPham, Trang
Wang, Paul
Wion, Emily
Yan, Ye
Yi, Stella S
Zhu, Lin
Investigators, MOSAAIC
Ahn, Jiyoung
Chen, Yu
Hayes, Richard
Yi, Stella
Doan, Lan
Newman, Jonathan
Fang, Carolyn Y
X., Grace
Zhu, Lin
Hu, Frank B
Aschebrook-Kilfoy, Briseis
Ahsan, Habibul
Kibriya, Muhammad
Kim, Karen
Randal, Fornessa
Hsing, Ann W
Kushida, Clete
Palaniappan, Latha
Wu, Joseph
Henderson, Victor
John, Esther M
Lu, Ying
Wang, Paul
Mau, Marjorie KLM
Maunakea, Alika K
Anderson, Garnet
Hsu, Li
Li, ShangJu
Mendoza, Jason
Beery, Danny
Carrick, William
Wion, Emily
Neuhouser, Marian
VoPham, Trang
Lampe, Johanna
Supervisor
Department
Epidemiology
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Type
Journal article
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Language
English
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Abstract
BACKGROUND: Asian American (AsA) and Native Hawaiian and Pacific Islander (NHPI) populations are underrepresented in U.S. health studies. OBJECTIVES: The MOSAAIC (Multi-ethnic Observational Study in American Asian and Pacific Islander Communities) is a cohort study designed to improve understanding of disparities in cardiovascular disease and other health conditions affecting AsA and NHPI groups. METHODS: Through broad eligibility criteria and outreach tailored to each study community, MOSAAIC will include 11,500 adults aged 18+ years living in 5 field center regions: New York, Philadelphia, Chicago, San Francisco Bay Area, and Honolulu. The protocol specifies sample-size targets to allow valid comparisons among persons having personal or family origins in 4 geographically defined regions, including East Asia (the largest groups being Chinese and Korean), South Asia (Indian), Southeast Asia (Vietnamese and Filipino) and Oceania (NHPI). Measurements to be obtained at an in-person examination include clinical laboratory tests, medical history, medication use, spirometry, cognitive and physical function, anthropometry, and electrocardiogram. Surveys in multiple languages to assess medical, behavioral, lifestyle, social and environmental influences on health were developed by a multistep process to ensure equivalency between translations and cultural appropriateness. Biospecimens are stored for future studies. Long-term follow-up will be conducted to ascertain and adjudicate major health events including myocardial infarction, stroke, heart failure, and mortality. CONCLUSIONS: The National Institutes of Health established MOSAAIC as a resource for wide-ranging epidemiologic investigation of factors related to cardiometabolic, pulmonary, or mental health in persons of diverse AsA and NHPI background.
Citation
J. Ahn, H. Ahsan, G.L. Anderson, B. Aschebrook-Kilfoy, D. Beery, W. Carrick , et al., "Design of MOSAAIC (Multi-Ethnic Observational Study in American Asian and Pacific Islander Communities)," JACC Asia, 2026, https://doi.org/10.1016/j.jacasi.2026.02.027.
Source
JACC Asia
Conference
Keywords
42 Health Sciences, 4206 Public Health, 3 Good Health and Well Being
Subjects
Source
Publisher
Elsevier
DOI
10.1016/j.jacasi.2026.02.027
Additional links
https://www.sciencedirect.com/science/article/pii/S2772374726001687
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