Improving consciousness assessment through neuroadaptive artificial intelligence and quantum-enhanced brain-computer interfaces
Oullier, Olivier Roser, Florian Barbaste, Paul Vasques, Xavier
Oullier, Olivier
Roser, Florian
Barbaste, Paul
Vasques, Xavier
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Human Computer Interaction
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Journal article
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English
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Abstract
Accurate assessment of consciousness in patients with disorders of consciousness (DoC) remains a major clinical challenge, particularly when motor impairment masks evidence of preserved awareness. Recent advances in neuroadaptive artificial intelligence (NA-AI) may help transform brain-computer interfaces (BCIs) from experimental systems into more clinically scalable tools tailored to each patient, continuously adjusting their models in real time to changes in an individual's (neuro)physiological signals. Generative and self-adapting AI models can account for inter-individual variability and temporal instability in neural signals, enabling faster calibration, improved robustness and personalized decoding of conscious intent. AI world-model approaches further enable realistic and dynamic representations of a patient's neurophysiology, allowing BCIs to interpret neural activity in the context of evolving brain states rather than static classifications of consciousness levels. Emerging work in quantum-enhanced machine and deep learning suggests that some current computational bottlenecks in BCIs, including high-dimensional optimization and complex pattern discovery, may be further alleviated. We argue that the convergence of neuroadaptive AI and quantum-enabled computation could improve the sensitivity, speed and reliability of consciousness assessments. Given the exploratory stage of quantum-AI research, rigorous clinical validation and governance frameworks will be required to ensure safe deployment and improved patient outcomes. If validated, quantum-AI BCIs could reduce diagnostic uncertainty, improve prognostication and support ethically grounded decision-making for patients unable to communicate.
Citation
O. Oullier, F. Roser, P. Barbaste, X. Vasques, "Improving consciousness assessment through neuroadaptive artificial intelligence and quantum-enhanced brain-computer interfaces," Clinical Neurology and Neurosurgery, vol. 266, pp. 109396-109396, 2026, https://doi.org/10.1016/j.clineuro.2026.109396.
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Clinical Neurology and Neurosurgery
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Keywords
32 Biomedical and Clinical Sciences, 3202 Clinical Sciences, 3209 Neurosciences
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Elsevier