Loading...
Consensus-Based Expert Recommendations on the Management of Hemophilia A in the Gulf Region
Alzahrani, Hazzaa Abdulla Warsi, Ashraf Mullah-Ali, Ali Alotaibi, Ghazi Abu-Riash, Mahmoud Alshahrani, Mohammad Siddiqui, Mustaqeem Owaidah, Tarek Hashmi, Shahrukh
Alzahrani, Hazzaa Abdulla
Warsi, Ashraf
Mullah-Ali, Ali
Alotaibi, Ghazi
Abu-Riash, Mahmoud
Alshahrani, Mohammad
Siddiqui, Mustaqeem
Owaidah, Tarek
Hashmi, Shahrukh
Supervisor
Department
Computer Vision
Embargo End Date
Type
Journal article
Date
2025
License
Language
English
Collections
Research Projects
Organizational Units
Journal Issue
Abstract
Background: Hemophilia A presents a significant health challenge in the Gulf region, where it has an especially high prevalence. There are several unmet needs associated with the management of hemophilia A in the region. The aim of this manuscript was to contextualize unmet management needs, provide recommendations to optimize care, and specify requirements for the establishment of gene therapy centers in the region.
Summary: An expert panel was assembled comprising ten clinical hematologists from Kuwait, Oman, Saudi Arabia, and the UAE. The Delphi methodology was used to obtain a consensus on statements relating to several aspects of hemophilia A. A consensus was reached for all statements by means of an online, anonymized voting system. The consensus statements pertain to screening and diagnosis, treatment approaches, and requirements for the implementation of gene therapy.
Key messages: There are significant challenges that hinder the optimal management of hemophilia A in the Gulf region. The consensus statements presented provide specific recommendations to improve diagnostic and treatment approaches, promote multidisciplinary care, and optimize regional data generation and reporting. These statements also delineate the requirements for the establishment of gene therapy centers for hemophilia A in the region.
Background: Hemophilia A presents a significant health challenge in the Gulf region, where it has an especially high prevalence. There are several unmet needs associated with the management of hemophilia A in the region. The aim of this manuscript was to contextualize unmet management needs, provide recommendations to optimize care, and specify requirements for the establishment of gene therapy centers in the region.
Summary: An expert panel was assembled comprising ten clinical hematologists from Kuwait, Oman, Saudi Arabia, and the UAE. The Delphi methodology was used to obtain a consensus on statements relating to several aspects of hemophilia A. A consensus was reached for all statements by means of an online, anonymized voting system. The consensus statements pertain to screening and diagnosis, treatment approaches, and requirements for the implementation of gene therapy.
Key messages: There are significant challenges that hinder the optimal management of hemophilia A in the Gulf region. The consensus statements presented provide specific recommendations to improve diagnostic and treatment approaches, promote multidisciplinary care, and optimize regional data generation and reporting. These statements also delineate the requirements for the establishment of gene therapy centers for hemophilia A in the region.
Citation
H. A. Alzahrani, A. Warsi, A. Mullah-Ali, G. Alotaibi, M. Abu-Riash, M. Alshahrani, et al., "Consensus-Based Expert Recommendations on the Management of Hemophilia A in the Gulf Region," Acta Haematologica, vol. 148, no. 1, pp. 91–104, 2025
Source
Acta Haematologica
Conference
Keywords
Haemophilia, Haematology, Bleeding disorders, Multidisciplinary care, Gene therapy
Subjects
Source
Publisher
KARGER